Short description: Vaccine against diphtheria, tetanus, whooping cough and polio

DTaP-IPV vaccine

DPT-IPV vaccine in Japan

Combination of
DTaP vaccine| Vaccine
Inactivated poliovirus vaccine| Vaccine
Clinical data
Trade names| Kinrix, Quadracel, Boostrix-IPV, Infanrix-IPV, others
Other names| diphtheria, tetanus, pertussis (acellular, component) and poliomyelitis (inactivated) vaccine (adsorbed, reduced antigen(s) content)
AHFS/Drugs.com| Kinrix Quadracel
Pregnancy
category|

* AU: A

Routes of
administration| Intramuscular injection
ATC code|

* J07CA02 (WHO)

Legal status
Legal status|

* In general: ℞ (Prescription only)

Identifiers
CAS Number|

* 1688606-07-6

DTaP-IPV vaccine is a combination vaccine whose full generic name is diphtheria and tetanus toxoids and acellular pertussis adsorbed and inactivated poliovirus vaccine (IPV).[1][2]

It is also known as DTaP/IPV, dTaP/IPV, DTPa-IPV, or DPT-IPV.[1] It protects against the infectious diseases diphtheria, tetanus, pertussis, and poliomyelitis.[1]

Branded formulations marketed in the USA are Kinrix from GlaxoSmithKline[3] and Quadracel from Sanofi Pasteur.[4]

Repevax is available in the UK.[5][6]

Within Japan, the formulation is called 四種混合（shishukongou - "mixture of 4"). Astellas markets it under the クアトロバック ('Quattro-back') formulation, while another is available from Mitsubishi Tanabe Pharma named テトラビック ('Tetrabic')[7].[8] A previous product by Takeda Pharmaceutical Company has been withdrawn by the company.[9]

## References

1. ↑ 1.0 1.1 1.2 "Diphtheria, Tetanus, Pertussis (Acellular, Component) And Poliomyelitis (Inactivated) Vaccine (Adsorbed)". Drugs.com. https://www.drugs.com/international/diphtheria-tetanus-pertussis-acellular-component-and-poliomyelitis-inactivated-vaccine-adsorbed.html.
2. ↑ "DTaP-IPV-HepB-Hib Vaccine (Hexyon®): An Updated Review of its Use in Primary and Booster Vaccination". Paediatric Drugs 21 (5): 397–408. October 2019. doi:10.1007/s40272-019-00353-7. PMID 31444785.
3. ↑ "Kinrix". US Food and Drug Administration. https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm172495.htm.
4. ↑ "Quadracel". US Food and Drug Administration. https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm439856.htm.
5. ↑ "Repevax, suspension for injection, in pre-filled syringe - Summary of Product Characteristics (SmPC) - (emc)". https://www.medicines.org.uk/emc/product/5580#gref.
6. ↑ "14. Vaccines". British National Formulary (BNF) (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 - March 2021. p. 1381. ISBN 978-0-85711-369-6.
7. ↑ "医療用医薬品 : テトラビック (テトラビック皮下注シリンジ)". https://www.kegg.jp/medicus-bin/japic_med?japic_code=00060717.
8. ↑ "医療用医薬品 : クアトロバック (クアトロバック皮下注シリンジ)". https://www.kegg.jp/medicus-bin/japic_med?japic_code=00060732.
9. ↑ "【武田薬品】４種混合ワクチンの開発中止‐ノロウイルスなどに資源投入｜薬事日報ウェブサイト". https://www.yakuji.co.jp/entry41529.html.

* v
* t
* e

Artificial induction of immunity / Immunization: Vaccines, Vaccination, Infection, Biology:Inoculat, Inoculation (J07)

Development|

* Adjuvants
* List of vaccine ingredients
* Mathematical modelling
* Timeline
* Trials

Classes|

* Conjugate vaccine
* DNA vaccination
* Inactivated vaccine
* Live vector vaccine
* Attenuated vaccine
* Heterologous vaccine
* Subunit/component / Peptide / Virus-like particle
* Toxoid

Administration|

* Global:
* GAVI Alliance
* Policy
* Schedule
* Vaccine injury
* USA:
* ACIP
* Vaccine court
* Vaccines for Children Program
* VAERS
* VSD

Vaccines|

| Bacterial|

* Anthrax
* Brucellosis
* Cholera#
* Diphtheria#
* Hib#
* Leptospirosis
* Lyme disease‡
* Meningococcus#
* MeNZB
* Medicine:NmVac4-A/C/Y/W-135
* Pertussis#
* Plague
* Pneumococcal#
* PCV
* PPSV
* Q fever
* Tetanus#
* Tuberculosis
* BCG#
* Typhoid#
* Ty21a
* ViCPS
* Typhus
* combination: DTwP/DTaP

|

Viral|

* Adenovirus
* Flu#
* H1N1 (Pandemrix)
* LAIV
* Hantavirus
* Hepatitis A#
* Hepatitis B#
* Hepatitis E
* HPV
* Cervarix
* Gardasil
* Japanese encephalitis#
* Measles#
* Mumps#
* Medicine:Mumpsvax
* Polio#
* Sabin
* Salk
* Rabies#
* Rotavirus#
* Rubella#
* Smallpox
* Medicine:Dryvax
* Tick-borne encephalitis
* Varicella zoster
* chicken pox#
* Zoster vaccine
* Yellow fever#
* combination:
* MMR
* MMRV
* research:
* Chikungunya
* Cytomegalovirus
* Dengue
* Ebola
* Epstein–Barr virus
* Hepatitis C
* HIV

Protozoan|

* Malaria
* RTS,S
* research:
* Trypanosomiasis

Helminthiasis|

* research:
* Hookworm
* Schistosomiasis

Other|

* Androvax (androstenedione albumin)
* Cancer vaccines
* ALVAC-CEA
* BCG#
* Hepatitis B#
* HPV
* Cervarix
* Gardasil
* PROSTVAC
* NicVAX
* Ovandrotone albumin (Fecundin)
* TA-CD
* TA-NIC
* combination
* DTaP-IPV/Hib
* DTaP-IPV-HepB
* Hexavalent vaccine
* Pentavalent vaccine

Controversy|

* General
* MMR
* NCVIA
* Pox party
* Thiomersal
* Vaccines and SIDS
* Lancet MMR autism fraud
* Cedillo v. Secretary of Health and Human Services
* Alternative vaccination schedule

Related|

* Epidemiology
* Eradication of infectious diseases
* Every Child by Two
* List of vaccine topics

* #WHO-EM
* ‡Withdrawn from market
* Clinical trials:
* †Phase III
* §Never to phase III

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