Protein-coding gene in the species Homo sapiens

LRATD2

Identifiers
Aliases| LRATD2, BCMP101, NSE2, family with sequence similarity 84 member B, FAM84B, LRAT domain containing 2
External IDs| OMIM: 609483 MGI: 3026924 HomoloGene: 18379 GeneCards: LRATD2
| Gene location (Human)

Chr.| Chromosome 8 (human)[1]

Band| 8q24.21| Start| 126,552,443 bp[1]
End| 126,558,478 bp[1]
| Gene location (Mouse)

Chr.| Chromosome 15 (mouse)[2]

Band| 15|15 D1| Start| 60,690,843 bp[2]
End| 60,725,627 bp[2]
| RNA expression pattern

Bgee| | Top expressed in

* parotid gland

* retinal pigment epithelium

* secondary oocyte

* renal medulla

* palpebral conjunctiva

* pancreatic epithelial cell

* cavity of mouth

* amniotic fluid

* renal cortex

* kidney

More reference expression data
BioGPS| | n/a

Orthologs
Species| Human| Mouse
Entrez| |

157638

399603

Ensembl| |

ENSG00000168672

ENSMUSG00000072568

UniProt| |

Q96KN1

D3YXJ5

RefSeq (mRNA)| |

NM_174911

NM_001162926
NM_207269

RefSeq (protein)| |

NP_777571

NP_001156398

Location (UCSC)| Chr 8: 126.55 – 126.56 Mb| Chr 15: 60.69 – 60.73 Mb
PubMed search| [3]| [4]
Wikidata
| View/Edit Human| View/Edit Mouse

|

Family with sequence similarity 84 member B is a protein that in humans is encoded by the FAM84B gene. [5]

## References[edit]

1. ^ a b c GRCh38: Ensembl release 89: ENSG00000168672 \- Ensembl, May 2017
2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000072568 \- Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: Family with sequence similarity 84 member B". Retrieved 2018-05-27.

## Further reading[edit]

* Pomerantz MM, Beckwith CA, Regan MM, Wyman SK, Petrovics G, Chen Y, Hawksworth DJ, Schumacher FR, Mucci L, Penney KL, Stampfer MJ, Chan JA, Ardlie KG, Fritz BR, Parkin RK, Lin DW, Dyke M, Herman P, Lee S, Oh WK, Kantoff PW, Tewari M, McLeod DG, Srivastava S, Freedman ML (July 2009). "Evaluation of the 8q24 prostate cancer risk locus and MYC expression". Cancer Res. 69 (13): 5568–74. doi:10.1158/0008-5472.CAN-09-0387. PMC 2884104. PMID 19549893.
* White KL, Sellers TA, Fridley BL, Vierkant RA, Phelan CM, Tsai YY, Kalli KR, Berchuck A, Iversen ES, Hartmann LC, Liebow M, Armasu S, Fredericksen Z, Larson MC, Duggan D, Couch FJ, Schildkraut JM, Cunningham JM, Goode EL (February 2010). "Variation at 8q24 and 9p24 and risk of epithelial ovarian cancer". Twin Res Hum Genet. 13 (1): 43–56. doi:10.1375/twin.13.1.43. PMC 2932441. PMID 20158306.
* Hsu FM, Cheng JC, Chang YL, Lee JM, Koong AC, Chuang EY (May 2015). "Circulating mRNA Profiling in Esophageal Squamous Cell Carcinoma Identifies FAM84B As A Biomarker In Predicting Pathological Response to Neoadjuvant Chemoradiation". Sci Rep. 5: 10291. doi:10.1038/srep10291. PMC 4434848. PMID 25980316.
* Cheng C, Cui H, Zhang L, Jia Z, Song B, Wang F, Li Y, Liu J, Kong P, Shi R, Bi Y, Yang B, Wang J, Zhao Z, Zhang Y, Hu X, Yang J, He C, Zhao Z, Wang J, Xi Y, Xu E, Li G, Guo S, Chen Y, Yang X, Chen X, Liang J, Guo J, Cheng X, Wang C, Zhan Q, Cui Y (2016). "Genomic analyses reveal FAM84B and the NOTCH pathway are associated with the progression of esophageal squamous cell carcinoma". GigaScience. 5: 1. doi:10.1186/s13742-015-0107-0. PMC 4709967. PMID 26759717.

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