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	Blood cyst;
	Blood cyst: The lesion was an incidental finding on the tricuspid valve of a 4-month-old infant who died of unrelated causes. The large size of the cyst (4 mm) and the age of the patient are unusual for congenital blood cysts, which are usually less than 2 mm in diameter and regress by 2 months of age. ; Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology

Synonyms and keywords: Congenital cardiac cyst, intracardiac cyst

Overview[edit | edit source]

Intracardiac blood cysts are thin-walled congenital cysts located in the endocardium and are seen predominantly in infants.^[1]^[2]^[3]^[4]^[5]^[6]^[7]^[8]^[9]^[10]^[11]^[12]^[13]^[14]^[15]^[16]^[17]^[18]^[19]^[20]^[21]

References[edit | edit source]

↑ Elsässer C. Bericht über die Ereignisse in der Gebäranstalt des Catherinen-Hospital im Jahre 1844. Med Correspondenzblatt 1844;14:297.
↑ Luschka H. Die Blutergüsse im Gewebe der Herzklappen. Virchows Arch Pathol Anat 1858;11:144-9.
↑ Burke A, Virmani R. Tumors of the heart and great vessels. Atlas of Tumor Pathology, 3rd Series, Fascicle 16. Washington, D.C. Armed Forces Institute of Pathology, 1996. pp.79-80.
↑ Pelikan HM, Tsang TS, Seward JB. Giant blood cyst of the mitral valve. J Am Soc Echocardiogr. 1999 Nov;12(11):1005-7.
↑ Boyd WC, Hartman GS, Reilly DM, Kreiger KH. An adult atrial blood cyst. J Cardiothorac Vasc Anesth. 1999 Oct;13(5):592-3.
↑ Minato H, Manabe T, Masaki H, Kawahara Y. Blood cyst of the pulmonary valve in an adult: report of a case and review of the literature. Hum Pathol 1997;28:252-5.
↑ Niinami H, Ishihara S, Hara S, Tanaka S, Yamaguti E, Takase S. Blood cyst with a calcium stone originating from the right atrial septum. Cardiovasc Surg 1996;4:260-2.
↑ Boyd TAB. Blood cysts on heart valves of infants. Am J Pathol 1949;25:757-9.
↑ Levinson SA, Learner A. Blood cysts on heart valves of new-born infants. Arch Pathol 1932;14:810-7.
↑ Pasaoglu I, Dogan R, Nazli N, Gungen Y, Bozer AY. Blood cyst originating from tricuspid septal leaflet. J Cardiovasc Surg (Torino) 1991;32:589-91.
↑ Pasaoglu I, Dogan R, Demircin M, Bozer AY. Blood cyst of the pulmonary valve causing pulmonic valve stenosis. Am J Cardiol 1993;72:493-4.
↑ Zimmerman KG, Paplanus SH, Dong S, Nagle RB. Congenital blood cysts of the heart valves. Hum Pathol 1983;14:699-703.
↑ Xie SW, Lu OL, Picard MH. Blood cyst of the mitral valve: detection by transthoracic and transesophageal echocardiography. J Am Soc Echocardiogr 1992;5:547-50.
↑ Arnold IR, Hubner PJ, Firmin RK. Blood filled cyst of the papillary muscle of the mitral valve producing severe left ventricular outflow tract obstruction. Br Heart J 1990;63:132-3.
↑ Kantelip B, Satge D, Camilleri L, Chenard MP, De Riberolles C. Valvular cyst and atrioventricular canal in a child with trisomy 21. Ann Pathol 1994;14:101-7.
↑ Roberts PF, Serra AJ, McNicholas KW, Shapira N, Lemole GM. Atrial blood cyst: a rare finding. Ann Thorac Surg 1996;62:880-2.
↑ Hauser AM, Rathod K, McGill J, et al. Blood cyst of the papillary muscle. Clinical, echocardiographic and anatomic observations. Am J Cardiol 1983; 51:612-3.
↑ DeGroff C, Silberbach M, Sahn DJ, Droukas P. Giant blood cyst of the aortic valve. J Am Soc Echocardiogr 1995; 8:543-5.
↑ Sim EK, Wong ML, Tan KT, Sim SK. Blood cyst of the tricuspid valve. Ann Thorac Surg 1996; 61:1012-3.
↑ Mohanty SR, Murthy KS, Krishnanaik S, Sivaraman A, Cherian KM. Cardiac blood-filled cyst at the atrialized portion of the right ventricle in a patient with Ebstein anomaly: a case report. J Thorac Cardiovasc Surg 2000; 120:422-3.
↑ Roberts PF, Serra AJ, McNicholas KW, Shapira N, Lemole GM. Atrial blood cyst: a rare finding. Ann Thorac Surg 1996; 62:880-2.

External Links[edit | edit source]

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[1] Elsässer C. Bericht über die Ereignisse in der Gebäranstalt des Catherinen-Hospital im Jahre 1844. Med Correspondenzblatt 1844;14:297.

[2] Luschka H. Die Blutergüsse im Gewebe der Herzklappen. Virchows Arch Pathol Anat 1858;11:144-9.

[3] Burke A, Virmani R. Tumors of the heart and great vessels. Atlas of Tumor Pathology, 3rd Series, Fascicle 16. Washington, D.C. Armed Forces Institute of Pathology, 1996. pp.79-80.

[4] Pelikan HM, Tsang TS, Seward JB. Giant blood cyst of the mitral valve. J Am Soc Echocardiogr. 1999 Nov;12(11):1005-7.

[5] Boyd WC, Hartman GS, Reilly DM, Kreiger KH. An adult atrial blood cyst. J Cardiothorac Vasc Anesth. 1999 Oct;13(5):592-3.

[6] Minato H, Manabe T, Masaki H, Kawahara Y. Blood cyst of the pulmonary valve in an adult: report of a case and review of the literature. Hum Pathol 1997;28:252-5.

[7] Niinami H, Ishihara S, Hara S, Tanaka S, Yamaguti E, Takase S. Blood cyst with a calcium stone originating from the right atrial septum. Cardiovasc Surg 1996;4:260-2.

[8] Boyd TAB. Blood cysts on heart valves of infants. Am J Pathol 1949;25:757-9.

[9] Levinson SA, Learner A. Blood cysts on heart valves of new-born infants. Arch Pathol 1932;14:810-7.

[10] Pasaoglu I, Dogan R, Nazli N, Gungen Y, Bozer AY. Blood cyst originating from tricuspid septal leaflet. J Cardiovasc Surg (Torino) 1991;32:589-91.

[11] Pasaoglu I, Dogan R, Demircin M, Bozer AY. Blood cyst of the pulmonary valve causing pulmonic valve stenosis. Am J Cardiol 1993;72:493-4.

[12] Zimmerman KG, Paplanus SH, Dong S, Nagle RB. Congenital blood cysts of the heart valves. Hum Pathol 1983;14:699-703.

[13] Xie SW, Lu OL, Picard MH. Blood cyst of the mitral valve: detection by transthoracic and transesophageal echocardiography. J Am Soc Echocardiogr 1992;5:547-50.

[14] Arnold IR, Hubner PJ, Firmin RK. Blood filled cyst of the papillary muscle of the mitral valve producing severe left ventricular outflow tract obstruction. Br Heart J 1990;63:132-3.

[15] Kantelip B, Satge D, Camilleri L, Chenard MP, De Riberolles C. Valvular cyst and atrioventricular canal in a child with trisomy 21. Ann Pathol 1994;14:101-7.

[16] Roberts PF, Serra AJ, McNicholas KW, Shapira N, Lemole GM. Atrial blood cyst: a rare finding. Ann Thorac Surg 1996;62:880-2.

[17] Hauser AM, Rathod K, McGill J, et al. Blood cyst of the papillary muscle. Clinical, echocardiographic and anatomic observations. Am J Cardiol 1983; 51:612-3.

[18] DeGroff C, Silberbach M, Sahn DJ, Droukas P. Giant blood cyst of the aortic valve. J Am Soc Echocardiogr 1995; 8:543-5.

[19] Sim EK, Wong ML, Tan KT, Sim SK. Blood cyst of the tricuspid valve. Ann Thorac Surg 1996; 61:1012-3.

[20] Mohanty SR, Murthy KS, Krishnanaik S, Sivaraman A, Cherian KM. Cardiac blood-filled cyst at the atrialized portion of the right ventricle in a patient with Ebstein anomaly: a case report. J Thorac Cardiovasc Surg 2000; 120:422-3.

[21] Roberts PF, Serra AJ, McNicholas KW, Shapira N, Lemole GM. Atrial blood cyst: a rare finding. Ann Thorac Surg 1996; 62:880-2.

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v t e Congenital malformations and deformations of circulatory system (Q20-Q28, 745-747)
Cardiac chambers and connections	Persistent truncus arteriosus - Double outlet right ventricle (Taussig-Bing syndrome) - Transposition of the great vessels (dextro, levo)
Cardiac septa	Ventricular septal defect - Atrial septal defect (Lutembacher's syndrome) - Atrioventricular septal defect (Ostium primum) - Tetralogy of Fallot - Eisenmenger's syndrome
Right: pulmonary and tricuspid valves	pulmonary valves (stenosis, insufficiency) - tricuspid valves (stenosis, atresia) - Ebstein's anomaly
Left: aortic and mitral valves	aortic valves (stenosis, insufficiency, bicuspid) - mitral valves (stenosis, regurgitation) - Hypoplastic left heart syndrome
Other congenital malformations of heart	Dextrocardia - Levocardia - Cor triatriatum
Great arteries	aorta (Patent ductus arteriosus, Aortic coarctation, Interrupted aortic arch, Overriding aorta, Aneurysm of sinus of Valsalva, Vascular ring) - Pulmonary atresia
Great veins	Persistent left superior vena cava - Total anomalous pulmonary venous connection - Scimitar syndrome
Other	Arteriovenous malformation (Cerebral arteriovenous malformation)
See also non-congenital conditions (I, 390-459)

v t e Symptoms and signs: circulatory (R00–R03, 785)
Cardiovascular	Template:Navbox subgroup
Myeloid/blood	Template:Navbox subgroup

v t e Symptoms and signs: respiratory system (R04–R07, 786)
Hemorrhage	Epistaxis Hemoptysis
Abnormalities of breathing	Respiratory sounds Stridor Wheeze Crackles Rhonchi Hamman's sign Apnea Dyspnea Hyperventilation/Hypoventilation Hyperpnea/Tachypnea/Hypopnea/Bradypnea Orthopnea/Platypnea Trepopnea Biot's respiration Cheyne-Stokes respiration Kussmaul breathing Hiccup Mouth breathing/Snoring Breath-holding
Other	Asphyxia Cough Pleurisy Sputum Respiratory arrest Hypercapnia/Hypocapnia Pectoriloquy: Whispered pectoriloquy Egophony Bronchophony Pleural friction rub Fremitus Silhouette sign
Chest, general	Chest pain Precordial catch syndrome

v t e Symptoms and signs: digestive system and abdomen (R10–R19, 787,789)
GI tract	Template:Navbox subgroup
Accessory	Hepatosplenomegaly/Hepatomegaly Jaundice
Abdominopelvic	Ascites
Abdominal – general	Abdominal pain (Acute abdomen, Colic, Baby colic) Splenomegaly Abdominal guarding · Abdominal mass · Rebound tenderness Shifting dullness · Bulging flanks · Puddle sign · Fluid wave test

v t e Symptoms and signs: Symptoms concerning nutrition, metabolism and development (R62–R64, 783)
Ingestion/Weight	decrease: Anorexia • Weight loss/Cachexia/Underweight increase: Polyphagia • Polydipsia • Orexigenia • Weight gain
Growth	Delayed milestone • Failure to thrive • Short stature (e.g., Idiopathic)


Blood cyst
Blood cyst: The lesion was an incidental finding on the tricuspid valve of a 4-month-old infant who died of unrelated causes. The large size of the cyst (4 mm) and the age of the patient are unusual for congenital blood cysts, which are usually less than 2 mm in diameter and regress by 2 months of age. Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology