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This editable Main Article is under development and subject to a disclaimer.

[edit intro]

Bradykinin receptors are "cell surface receptors that bind bradykinin and related kinins with high affinity and trigger intracellular changes which influence the behavior of cells. The identified receptor types (B-1 and B-2, or BK-1 and BK-2) recognize endogenous kallidin; t-kinins; and certain bradykinin fragments as well as bradykinin itself."[1]

Bradykinin receptors are G-Protein-coupled cell surface receptors.

## Contents

* 1 Classification
* 1.1 Bradykinin B1 receptor
* 1.2 Bradykinin B2 receptor
* 2 References

## Classification[edit]

### Bradykinin B1 receptor[edit]

"A subtype of bradykinin receptor that is induced in response to inflammation. It may play a role in chronic inflammation and has a high specificity for kinins lacking the C-terminal arginine such as des-Arg(10)-kallidin and des-Arg(9)-bradykinin. The receptor is coupled to G-Protein, GQ-G11 alpha family and G-Protein, GI-GO alpha family signaling proteins."[2]

### Bradykinin B2 receptor[edit]

"A constitutively expressed subtype of bradykinin receptor that may play a role in the acute phase of the inflammatory and pain response. It has high specificity for intact forms of bradykinin and kallidin. The receptor is coupled to G-Protein, GQ-G11 alpha family and G-Protein, GI-GO alpha family signaling proteins."[3]

## References[edit]

1. ↑ Anonymous (2023), Bradykinin receptor (English). Medical Subject Headings. U.S. National Library of Medicine.
2. ↑ Anonymous (2023), Bradykinin B1 receptor (English). Medical Subject Headings. U.S. National Library of Medicine.
3. ↑ Anonymous (2023), Bradykinin B2 receptor (English). Medical Subject Headings. U.S. National Library of Medicine.