HIV-2 retropepsin

Identifiers
EC no.| 3.4.23.47
CAS no.| 144114-21-6
Databases
IntEnz| IntEnz view
BRENDA| BRENDA entry
ExPASy| NiceZyme view
KEGG| KEGG entry
MetaCyc| metabolic pathway
PRIAM| profile
PDB structures| RCSB PDB PDBe PDBsum
| Search

PMC| articles
PubMed| articles
NCBI| proteins

HIV-2 retropepsin (EC 3.4.23.47) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Endopeptidase for which the P1 residue is preferably hydrophobic

This enzyme belongs to the peptidase family A2.

## References[edit]

1. ^ Tözsér J, Bláha I, Copeland TD, Wondrak EM, Oroszlan S (April 1991). "Comparison of the HIV-1 and HIV-2 proteinases using oligopeptide substrates representing cleavage sites in Gag and Gag-Pol polyproteins". FEBS Letters. 281 (1–2): 77–80. doi:10.1016/0014-5793(91)80362-7. PMID 2015912.
2. ^ Chen Z, Li Y, Chen E, Hall DL, Darke PL, Culberson C, Shafer JA, Kuo LC (October 1994). "Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases". The Journal of Biological Chemistry. 269 (42): 26344–8. PMID 7929352.

## External links[edit]

* HIV-2+retropepsin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

* v
* t
* e

Proteases: aspartate proteases (EC 3.4.23)

Vertebrate|

* Pepsin
* Chymosin
* Renin
* Signal peptide peptidase
* Beta secretase
* 1
* 2

Pathogenic|

* Plasmepsin
* HIV-1 protease

Plant|

* Nepenthesin

Cathepsin|

* D
* E

* v
* t
* e

Enzymes

Activity|

* Active site
* Binding site
* Catalytic triad
* Oxyanion hole
* Enzyme promiscuity
* Diffusion-limited enzyme
* Coenzyme
* Cofactor
* Enzyme catalysis

Regulation|

* Allosteric regulation
* Cooperativity
* Enzyme inhibitor
* Enzyme activator

Classification|

* EC number
* Enzyme superfamily
* Enzyme family
* List of enzymes

Kinetics|

* Enzyme kinetics
* Eadie–Hofstee diagram
* Hanes–Woolf plot
* Lineweaver–Burk plot
* Michaelis–Menten kinetics

Types|

* EC1 Oxidoreductases (list)
* EC2 Transferases (list)
* EC3 Hydrolases (list)
* EC4 Lyases (list)
* EC5 Isomerases (list)
* EC6 Ligases (list)
* EC7 Translocases (list)

Portal:

* Biology

*[v]: View this template
*[t]: Discuss this template
*[e]: Edit this template