Calpain-1

Identifiers
EC no.| 3.4.22.52
CAS no.| 78990-62-2
Databases
IntEnz| IntEnz view
BRENDA| BRENDA entry
ExPASy| NiceZyme view
KEGG| KEGG entry
MetaCyc| metabolic pathway
PRIAM| profile
PDB structures| RCSB PDB PDBe PDBsum
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PMC| articles
PubMed| articles
NCBI| proteins

Calpain-1 (EC 3.4.22.52, mu-calpain, calcium-activated neutral protease I) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Broad endopeptidase specificity

This enzyme belongs to the peptidase family C2.

## See also[edit]

* CAPN1

## References[edit]

1. ^ Dutt P, Spriggs CN, Davies PL, Jia Z, Elce JS (October 2002). "Origins of the difference in Ca2+ requirement for activation of mu- and m-calpain". The Biochemical Journal. 367 (Pt 1): 263–9. doi:10.1042/bj20020485. PMC 1222847. PMID 12014988.

## External links[edit]

* Calpain-1 at the US National Library of Medicine Medical Subject Headings (MeSH)

* v
* t
* e

Proteases: cysteine proteases (EC 3.4.22)

Caspase|

* Caspase 1
* Caspase 2
* Caspase 3
* Caspase 4
* Caspase 5
* Caspase 6
* Caspase 7
* Caspase 8
* Caspase 9
* Caspase 10
* Caspase 12
* Caspase 13
* Caspase 14

Fruit-derived|

* Papain
* Ficain
* Bromelain
* Actinidain

Calpain|

* CAPN1
* CAPN2
* CAPN3
* CAPN5
* CAPN6
* CAPN7
* CAPN8
* CAPN9
* CAPN10
* CAPN11
* CAPN12
* CAPN13
* CAPN14
* CAPNS1
* CAPNS2

Cathepsin|

* B
* C
* F
* H
* K
* L1/L2
* O
* S
* W
* Z

Other|

* Clostripain
* Cancer procoagulant
* Separase
* Autophagin
* Cruzipain
* 3C-like protease
* Gingipain R
* Gingipain K

* v
* t
* e

Enzymes

Activity|

* Active site
* Binding site
* Catalytic triad
* Oxyanion hole
* Enzyme promiscuity
* Diffusion-limited enzyme
* Coenzyme
* Cofactor
* Enzyme catalysis

Regulation|

* Allosteric regulation
* Cooperativity
* Enzyme inhibitor
* Enzyme activator

Classification|

* EC number
* Enzyme superfamily
* Enzyme family
* List of enzymes

Kinetics|

* Enzyme kinetics
* Eadie–Hofstee diagram
* Hanes–Woolf plot
* Lineweaver–Burk plot
* Michaelis–Menten kinetics

Types|

* EC1 Oxidoreductases (list)
* EC2 Transferases (list)
* EC3 Hydrolases (list)
* EC4 Lyases (list)
* EC5 Isomerases (list)
* EC6 Ligases (list)
* EC7 Translocases (list)

Portal:

* Biology

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