Major depressive disorder Microchapters

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Major Depressive Disorder (Patient Information)

Overview

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Pathophysiology

Causes

Differentiating Major depressive disorder from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Substance/Medication-induced Depressive Disorder

Depressive Disorder due to a Medical Condition

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Diagnostic Criteria

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Treatment

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ECT

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Primary Prevention

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Cost-Effectiveness of Therapy

Future or Investigational Therapies

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:  Mitra Chitsazan, M.D.[2]

## Overview[edit | edit source]

The one-year prevalence of major depressive disorder is approximately 7,000 per 100,000 (7%) of the overall population with marked differences by age groups.

## Epidemiology and Demographics[edit | edit source]

### Incidence[edit | edit source]

* The annual incidence (the number of new cases) of a major depressive episode has been estimated as 1.59% (1.89% in women and 1.10% in men). [1]

### Prevalence[edit | edit source]

* The twelve-month prevalence of major depressive disorder is 7,000 per 100,000 (7%) of the overall population.[1]

### Age[edit | edit source]

* There are marked differences by age groups; for example, the prevalence of major depressive disorder in individuals aged 18-29-year-old is x3 higher than the prevalence in the individuals aged 60-year-old and more. In individuals with the onset of major depressive disorder in early adolescence, the prevalence is 1.5- to 3-fold higher in females than in males. [1]

### Gender[edit | edit source]

* Major depressive disorder is more common in women. [1]

### Sociocultrural[edit | edit source]

* Depressive disorders are more common among single and divorced individuals compared with married individuals. [1]
* There is no association between depressive disorders and socioeconomic status or religion.

### Race[edit | edit source]

* There is no racial predilection to depressive disorders. [1]

## References[edit | edit source]

1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Diagnostic and statistical manual of mental disorders : DSM-5. Washington, D.C: American Psychiatric Association. 2013. ISBN 0890425558.